Agriculture: Grape Pest Management Guidelines

General Properties of Fungicides Used in Grapes

Common name
(example trade name)
Chemical class Activity Mode of action
(FRAC group number1)
Resistance potential Comments
azoxystrobin (Abound) QoI5 contact, systemic2 single-site (11) high3  
Bacillus pumilis (Sonata) biological-bacteria contact BM 02 low  
Bacillus subtilis (Serenade) biological-bacteria contact BM 02 low  
boscalid/pyraclostrobin (Pristine) SDHI6 and Qol5 contact, systemic2 single-site/
single-site (11/7)
high  
captan phthalimide contact multi-site (M4) low highly toxic to honey bee larvae
copper inorganic contact multi-site (M1) low  
copper hydroxide inorganic contact multi-site (M1) low  
copper sulfate inorganic contact multi-site (M1) low  
cyflufenamid (Torino) phenylacetamide contact unknown (U6) high  
cyprodinil (Vangard) anilinopyrimidine mostly contact, slightly systemic (on most crops) single-site (9) high3  
cyprodinil/fludioxonil (Switch) anilinopyrimidine and phenylpyrrole contact, slightly systemic single-site/
single-site (9/12)
low to medium  
difenoconazole/azoxystrobin (Quadris Top) DMI4-triazole and QoI5 contact and systemic (local) 2 single-site/
single-site (3/11)
medium to high  
difenoconazole/cyprodinil (Inspire Super) DMI4 and anilinopyrimidine contact, systemic2 single-site/
single-site (3/9)
medium  
fenhexamid (Elevate) hydroxyanilide Contact single-site (17) high3  
fluopyram/tebuconazole (Luna Experience) SDHI6 pyridinyl-ethyl-benzamide and DMI4 contact, systemic2 single-site/
single-site (7/3)
medium  
fungicidal soap (M-Pede) inorganic salt Contact low  
iprodione (Rovral) dicarboximide systemic (local) single-site? (2) low to medium  
kresoxim-methyl (Sovran) Qol5 contact, systemic2 single-site (11) high3  
mancozeb (Dithane) dithiocarbamate contact multi-site (M3) low  
mefenoxam (Ridomil Gold) phenylamide contact, systemic single-site (4) high3  
metrafenone (Vivando) benzophenone contact singe-site (50) high  
myclobutanil (Rally) DMI4-triazole systemic (local)2 single-site (3) high  
oil (JMS stylet oil) mineral oil contact various (NC) low  
potassium bicarbonate (Armicarb, Kaligreen, Milstop) inorganic salt contact various (NC) low  
pyrimethanil (Scala) anilinopyrimidine mostly contact, slightly systemic (on most crops) single-site (9) high3  
quinoxyfen (Quintec) quinoline contact single-site (13) medium to high  
sulfur inorganic contact multi-site (M2) low highly toxic to native strains of western predatory mite (Galen-dromus occidentalis) and parasites.
tebuconazole (Elite) DMI4-triazole systemic (local)2 single-site (3) high  
tetraconazole (Mettle) DMI4-triazole systemic (local)2 single-site (3) high  
thiophanate-methyl (Topsin) MBC7 systemic (local) single-site (1) very high3  
trifloxystrobin (Flint) Qol5 contact, systemic2 single site (11) high3  
triflumizole (Procure) DMI4-imidazole systemic (local)2 single-site (3) high  
ziram dithiocarbamate contact multi-site (M3) low  
1 Group numbers are assigned by the Fungicide Resistance Action Committee (FRAC) according to different modes of action. Fungicides with different group numbers are suitable to alternate in a resistance management program. In California, make no more than one application of a fungicide with a mode-of-action group number associated with high resistance risk before rotating to a fungicide with a different mode-of-action group number; for other fungicides, make no more than two consecutive applications before rotating to fungicide with a different mode-of-action group number.
2 Generally considered to have systemic action based on performance data but this characteristic may not have been proven experimentally using more rigorous assays.
3 Resistance has been found in California for certain fungicides with a single-site mode of action. To reduce the risk of resistance development, take the mode of action into account when choosing a fungicide. At the beginning of a treatment program, use a fungicide with a multi-site mode of action; for subsequent applications rotate or mix fungicides with different mode of action FRAC numbers. Use labeled rates (preferably the upper range) of the single-site fungicides, and limit the total number of applications per season.
4 DMI = demethylation (sterol) inhibitor
5 Qol = quinone outside inhibitor (strobilurin)
6 SDHI = succinate dehydrogenase inhibitor
7 MBC = methyl benzimidazole carbamate
—  = unknown
NC = not classified

Acknowledgment: Adaskaveg et al., 2022. Fungicides, Bactericides, Biocontrols, and Natural Products for Deciduous Tree Fruit and Nut, Citrus, Strawberry, and Vine Crops in California. (PDF)

Text Updated: 12/14
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